Clinical Trials Search

Search registered trials on ClinicalTrials.gov: phase, recruitment status, conditions, interventions, enrolment, sponsor and dates.

Pay by wallet (x402) clinical-trials-search

Example

Input

{
  "query": "crispr cas9",
  "limit": 3
}

Answer

{
  "query": "crispr cas9",
  "studies": [
    {
      "url": "https://clinicaltrials.gov/study/NCT03872479",
      "title": "Single Ascending Dose Study in Participants With LCA10",
      "nct_id": "NCT03872479",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "status": "UNKNOWN",
      "conditions": [
        "Leber Congenital Amaurosis 10"
      ],
      "enrollment": 34,
      "start_date": "2019-09-26",
      "study_type": "INTERVENTIONAL",
      "lead_sponsor": "Editas Medicine, Inc.",
      "interventions": [
        {
          "name": "EDIT-101",
          "type": "DRUG"
        }
      ],
      "location_count": 5,
      "completion_date": "2025-05-23",
      "enrollment_type": "ESTIMATED",
      "lead_sponsor_class": "INDUSTRY"
    }
  ],
  "returned": 1,
  "status_filter": null,
  "total_results": 103
}

Inputs

Field	Type	Required	What it is
`limit`	integer	No	Studies to return, 1-20. Default: 10
`query`	string	Yes	Search terms — a condition, intervention, sponsor or free text
`status`	string	No	Optional recruitment filter: recruiting, not_yet_recruiting, active_not_recruiting, completed, terminated, withdrawn, suspended

Output fields

How reliably each field appears in a successful answer.

Field	Type	Appears
`query`	string	Always (present in every successful answer)
`studies`	array	Always (present in every successful answer)
`returned`	number	Always (present in every successful answer)
`status_filter`	string	Always (present in every successful answer)
`total_results`	number	Always (present in every successful answer)

How to call it

The same tool through each route. MCP clients reach it through Strale’s server at https://api.strale.io/mcp; the call below is what the agent sends.

# Needs an API key. max_price_cents caps what this call may cost.
curl -X POST https://api.strale.io/v1/do \
  -H "Authorization: Bearer $STRALE_API_KEY" \
  -H 'Content-Type: application/json' \
  -d '{
    "capability_slug": "clinical-trials-search",
    "inputs": {
      "query": "crispr cas9",
      "limit": 3
    },
    "max_price_cents": 3
  }'

{
  "tool": "strale_execute",
  "arguments": {
    "slug": "clinical-trials-search",
    "inputs": {
      "query": "crispr cas9",
      "limit": 3
    },
    "max_price_cents": 3
  }
}

import { Strale } from "straleio";

const strale = new Strale({ apiKey: process.env.STRALE_API_KEY! });
const result = await strale.do({
  capability_slug: "clinical-trials-search",
  inputs: {
    "query": "crispr cas9",
    "limit": 3
  },
  max_price_cents: 3,
});

import os
from straleio import Strale, DoRequest

strale = Strale(api_key=os.environ["STRALE_API_KEY"])
result = strale.do(DoRequest(
    capability_slug="clinical-trials-search",
    inputs={
        "query": "crispr cas9",
        "limit": 3,
    },
    max_price_cents=3,
))

# No account. The first request answers 402 with the price in USDC;
# an x402 client pays it from your wallet and repeats the request.
curl -i -X POST https://api.strale.io/x402/v2/clinical-trials-search \
  -H 'Content-Type: application/json' \
  -d '{
    "query": "crispr cas9",
    "limit": 3
  }'

Limitations

Covers the ClinicalTrials.gov registry only
Trials registered solely with the EU Clinical Trials Information System, ISRCTN, the WHO ICTRP or a national registry do not appear. Registration is voluntary in many jurisdictions, so absence from this registry is not evidence a trial does not exist.
Registration record, not results
The response describes what the sponsor registered — design, enrolment target and status. It carries no outcome data, and a large share of registered trials never post results.
Status is sponsor-maintained and often stale
Recruitment status is whatever the sponsor last submitted. A status of UNKNOWN means the sponsor has not verified the record within the registry's expected window; completed trials are frequently left as recruiting for months.
Enrolment counts mix estimates with actuals
enrollment_type distinguishes ESTIMATED (a target) from ACTUAL (what was reached). Treating an estimated figure as achieved enrolment overstates a trial's size.